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apalutamide will lessen the extent or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medicines which can be CYP3A4 substrates may end up in lessen publicity to these drugs.DISCLAIMER The contents of the Site are for i